TB-500 (for purchase and use in Australia) is a synthetically produced version of the naturally occurring peptide known as Thymosin Beta 4. Thymosin Beta 4 is usually found in and around sites of injury or cell damage in the body. It was discovered that this peptide played a significant role in wound repair and cell regeneration.
In earlier years, TB-500 was developed as an alternative to Thymosin Beta 4 Peptide due to the high molecular weight and limited supply of the latter peptide. Thymosin Beta 4 and its synthetic version, TB-500, possess the same chemical makeup and produce almost similar effects in the body.
TB-500 was originally used in racing horses to bolster wound healing and prevent scarring and adhesion. Apparently, the use of TB-500 gave the horses an obvious advantage over their counterparts, and it was soon noticed by the regulatory bodies of the horse racing circuit.
Currently, there is a lot of speculation about the potential benefits that can be gained from using TB-500. This compound has caught the attention of bodybuilders, athletes, and fitness enthusiasts who are looking for alternative sources of pain management.
In this article, we will take a look at the following;
- What is TB-500?
- What are the potential effects of TB-500?
- How does it work?
- Safety and side effects
What Is TB-500?
TB-500 is a synthetically produced peptide that consists of a chain of 29 amino acids. It was created in the likeness of Thymosin Beta 4, a peptide that is produced by the thymus gland in the body.
Thymosin Beta 4 is present in tissues such as the lungs, brain, spleen, heart, and blood cells. It can also be found in the fluid present in wounds and other bodily fluids like saliva.
TB-500 has a much lower molecular weight compared to Thymosin Beta 4 and, as such, is a much-preferred alternative to the natural peptide.
What Are The Potential Effects of TB-500?
Numerous studies conducted on animals and a few clinical human trials have shown that TB-500 has the potential to produce many life-enhancing effects in the human body. Among the potential positive impacts of TB-500 are;
Promotion of Wound Healing
TB-500 has been found to cause a significant decrease in the time needed to heal wounds and repair cell damage. It can also help speed up the healing of injuries in otherwise slowly healing sites such as tendons and ligaments.
In a study, subjects suffering from pressure ulcers and stasis ulcers were reported to have benefited greatly from the topical application of TB-500.
Regeneration of Cardiac Muscles
In a study conducted with people who had previously suffered heart attacks as subjects, TB-500 was found to cause a noticeable difference in the muscles of the heart. There was an increase in the heart’s contractility and a reversal of functional loss.
TB-500 may also cause the inhibition of inflammation, reduce scar formation and prevent the death of cells in the heart.
Management of Inflammation
Inflammation is an essential phase of wound healing that facilitates the function of cell repairing components in the body. However, excessive and prolonged inflammation can hinder movement and reduce your performance.
TB-500 has been discovered to help curtail inflammation while promoting the activities of wound repairing compounds such as collagen.
Control of Infection
Infection or sepsis is the body’s response to the invasion of pathogens such as bacteria and viruses. Infection can lead to tissue breakdown and organ damage if not adequately treated.
TB-500 was used as a form of therapy for eye infections and dry eye syndrome. It was discovered that the peptide helped to reduce secretions while promoting regeneration in the affected eye.
Reversal of Aging Signs
A preliminary review of the effects of TB-500 revealed that the compound could potentially cause a reversal of aging signs in the body system and organs such as the heart and the brain.
TB-500 can, in theory, help remind adult cells of their young and proliferative phase, thereby prompting them to repair the signs of wear and tear in organs that might have occurred as a result of aging.
How Does It Work?
TB-500 works by promoting the actions of actin. Actin is a protein that is majorly responsible for cell regeneration, division, and proliferation. It is also responsible for the formation of blood vessels and endothelial cells. All of these mechanisms are highly crucial to wound healing and the repair of injured cells.
The synthetic peptide has also been found to inhibit the actions of F-actinemia, a compound that is responsible for infection and sepsis in the body.
TB-500 is also said to aid the regeneration of the heart muscles by causing a thickening of the epicardial muscle layer at the site of myocardial infarction as well as the healthy parts of the heart.
Safety and Side Effects
The use of TB-500 in racing horses produced no recorded long-term side effects. Similarly, test subjects who had TB-500 administered over the course of 6 to 8 weeks showed no fatal or life-altering side effects.
However, human users of the synthetic peptide reported a slight headache upon administration of the drug, which subsided soon after. Some people also reported developing flu-like symptoms that cleared up after a few days.
Other potential side effects can include fatigue, pain at the injection site, and nausea.
TB-500 is a synthetic compound produced to mimic the actions of the peptide Thymosin Beta 4, which occurs naturally in the body.
Among its potential benefits are rapid wound healing, reduction of inflammation, regeneration of the heart muscles, infection control, and reversal of aging effects.
TB-500 primarily works by facilitating the uptake of actin and thereby promoting the actions of wound healing components and repair of damaged cells. It has also been discovered to reverse the effects of cardiac attacks and myocardial infarction on the heart muscles.
TB-500 is considered relatively safe for human use as there have been no reports of severe adverse effects in human test subjects. Although recreational users have reported a few side effects, they are usually mild and require no medical intervention.