GHRP-2 (Pralmorelin) is a short hexapeptide that stimulates growth hormone release in healthy adult subjects. Made up of only 6 amino acids GHRP-2 makes it easier for subjects to build muscle mass and lose fatty deposits.
It is a synthetic agonist of ghrelin, the newly-discovered gut peptide that binds to the growth hormone secretagogue receptor. Ghrelin has been shown to have two major effects, stimulating both growth hormone secretion and appetite/meal initiation.
This means that a subject taking GHRP-2 will both increase the amount of growth hormone secreted by the pituitary gland, and gain all the associated benefits in lean muscle growth and weight loss associated with this increase, and increase a subject’s hunger.
However, this increase in hunger is much less significant than that associated with GHRP-6. It reduces the hunger attributes often associated with GHRP-6 significantly meaning it was not suitable for increasing food intake in healthy men even though it results in increased hunger.
It was also under investigation for the treatment of GHD and pituitary dwarfism and made it to phase II clinical trials for these indications.
GHRP-2 has also been reported to result in higher libido, better skin, and hair quality among other attributes.
GHRP-2 is sold in vials containing 5MG of lyophilised powder which can be reconstituted by adding a convenient amount of sterile or bacteriostatic water.
GHRP-2 is sold in vials containing 5MG of lyophilised powder which should be stored under refrigeration. (It is acceptable however for them to be mailed unrefrigerated). The contents can be reconstituted by adding a convenient amount of sterile or bacteriostatic water.
5mg of powder
2.5ml of bacteriostatic water
equals 2,000 mcg/ml
At time of dosing, an insulin syringe is used to draw and then inject the desired amount.
In the above example, a 100 mcg dose would require only 0.05 mL, or “5 IU” as marked on an insulin syringe. A 300 mcg would require 0.15 mL, or “15 IU” as marked on an insulin syringe.
Injection may be subcutaneous or intramuscular according to personal preference.
Dosing will ordinarily be at least twice per day and preferably 3 times per day for best effect, taken at least 30-60 minutes before a meal and at a time of non-elevated blood sugar (in other words, after blood sugar has had time to fall since the most recent meal.) The amount taken generally will be from 50-300 mcg at a time.
For increase in GH levels, higher doses within the suggested range definitely increase effect. With regard to healing benefit, for example for tendonitis, the low end of the range is often entirely sufficient and noticeably greater effect is not necessarily seen with increased dose.
While there is no sharp cut-off between a solution of GHRP-2 still being good and having lost potency with time, as a general guideline, a vial should be used within a month of having been reconstituted.
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