The Most Popular SARMS for Bulking – and How They Work

The Most Popular SARMS for Bulking - and How They Work


Bodybuilding is now a norm and not just something done by only a few individuals. And that means SARMs are also in higher demand than before.

SARMs are widely known to produce powerful bulking results with fewer side effects. They are also very selective when binding to androgen receptors unlike anabolic steroids.

This discriminative mechanism of action makes them a good supplement for bodybuilders, fitness lovers, and models despite being banned from public use.

Of the several SARM products on the market, only a few have gained prominence.

So if you

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would like to pick from a list of the most popular SARMs for bulking, this article is for you.

5 Most Popular SARMs For Bulking (And How They Get Job Done)

SARMs are alternative products to anabolic steroids designed to produce the same bulking results in the body without any health complications. And they do that by binding to androgen receptors found only in the bone and muscle tissues.

Here is a list of the most reputable SARMs in 2022 and how they work:


RAD-140, also known as testolone, along with buying MK-677 in Australia, tops this list as the most popular SARMs for bulking in 2022. In fact, you can consider it the best for bulking among many other non-steroidal anabolics.

How Does It Work?

Testolone selectively binds to androgen receptors in the bone and muscle tissues to mimic the actions of testosterone – a natural hormone in the body. After binding, it initiates some molecular reactions that lead to nitrogen retention in the body.

As a result, the proteins necessary for muscle growth are synthesized. Also, testolone provides an energy boost for sustained workouts and intense powerlifting. While testolone does not focus on cutting, you can still lose about 5 to 7 pounds of fat through sustained exercise.

Possible Side Effects

Although SARMs do not have severe side effects, there are still some things to look out for. Nausea, aggression, and testosterone suppression are the most common adverse effects.

Most users report up to 70% testosterone suppression, but this is not an issue. You can use post-cycle therapy (PCT) to restore your testosterone to normal levels.

Ligandrol 4033

Ligandrol 4033, also known as VK5211, was initially manufactured by Ligand pharmaceuticals to cure muscle degeneration in aged people and breast cancer patients. Aside from testolone, Ligandrol is the second most effective SARM product for bulking.

How Does It Work?

LGD 4033 follows the same mechanism as testolone by binding to the androgen receptors in muscle tissue. Unlike anabolic steroids, ligandrol does not trigger severe side effects like liver toxicity that results from indiscriminate binding.

The result of ligandrol is most notable in muscle development, with a gain of almost 15 pounds after an eight weeks cycle. LGD is not particularly effective for cutting, but it can help you lose about 3 – 5 lbs. of fat and increase muscle vascularity.

Possible Side Effects

Like testolone, you might experience nausea and increased blood pressure in the first few days of using Ligandrol. Testosterone suppression is also a significant downside of LGD, but it can be treated with PCT.

Ostarine MK-2866

Ostarine MK-2866 or Enobosarm, is a relatively mild SARM compared to others on the list. It was manufactured by GTx pharma and has a good reputation among fitness enthusiasts due to its less demanding side effects.

How Does It Work?

Once ostarine binds to the androgen receptors in place of testosterone, it initiates some DNA level activities which yield noticeable muscle growth.

While ostarine works like other SARMs, it has milder results. But this is good news since the risk of side effects and health complications is also minimal. Also, ostarine gives you a good burst of energy to last longer in your daily workout sessions. Moreover, it reduces your recovery time and facilitates the repair of damaged fibers.

Possible Side Effects

Users of ostarine report milder testosterone suppression compared to the 70% seen in testolone and other bulking SARMS. You might experience a slight headache, which typically subsides after two to three days.

Andarine S-4

Andarine is one of the rapidly growing SARMs in the bodybuilding community. S-4 was initially known to prevent muscle dystrophy, but recent research shows it can do more than that.

How Does It Work?

Andarine targets the androgen receptors in skeletal muscles and causes nitrogen retention for increased protein synthesis while blocking the effects of myostatin – a muscle growth inhibitor.

S-4 also reduces glucose uptake and enhances fat metabolism, thus contributing to weight loss and a petite display of well-streamlined abs – a good pick for models.

Possible Side Effects

Andarine S-4 is not ranked first despite its immense benefits because it can cause liver impairment, especially in people with previous health issues. It is also much more expensive than other SARMs on the market. Regardless, andarine is highly sought after by many bodybuilders and powerlifters.


Stenabolic (SR-9009), also known as Rev-Erba, was developed at the Scripps Research Institute by Professor Thomas Burris. While it does not contribute much to bulking like other listed SARMs, SR-9009 is still well-known for its resourceful working mechanisms.

How Does It Work?

SR-9009 interacts with androgen receptors in muscle tissue and sets off a chain of events that aids muscle development. Stenabolic SARM activates Rev-Erb transcription factors and AMPK (AMP-Activated Protein Kinase). Rev-Erb and AMPK regulate metabolism and increase fat burning to produce lean muscle mass.

Other than this, SR-9009 can increase the number of mitochondria in muscle cells to facilitate more energy production and intense workouts.

Possible Side Effects

Stenabolic SARM is rarely associated with any significant side effects. But you should expect minor gastrointestinal disturbances, which usually resolve in a few days.


Note that the list here does not include all the existing bulking SARMs, but it should give you a clear understanding of the most popular ones.

If used properly, any of these SARMs can help you achieve your fitness and bodybuilding goals. So, make your choice and place the order today.